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Laminae of fibroblasts and keratinocytes in the treatment of chronic ulcers refractory to standard therapies.

Chronic ulcers of lower limbs are a huge cost to the national health system and to the patient. Often these injuries are refractory to standard medical and surgical devices, persisting or relapsing in the short term.

Through advanced biomedical engineering studies, now laminae of keratinocytes and fibroblasts are available from donor sterilized and purified that, thanks also to a hyaluronic acid component, are able to induce the healing of chronic ulcers even in some of the most resistant cases.3

(3) Pajardi G, Rapisarda V, Somalvico F, Scotti A, Russo GL, Ciancio F, Sgrò A, Nebuloni M, Allevi R, Torre ML, Trabucchi E, Marazzi M. Skin substitutes based on allogenic fibroblasts or keratinocytes for chronic wounds not responding to conventional therapy: a retrospective observational study. Int Wound J. 2014 Feb12. doi: 10.1111/iwj.12223.

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